Address Infection Risk In 3 Main Bacterial Reservoirs—The Nose, Mouth & Skin

Comprehensive Nose To Toes™ pre-op prepping

Endogenous flora is the #1 source of pathogens that cause SSIs and it’s not limited to the skin. On the morning of surgery, prep your patients with the Nose To Toes system to help reduce the risk of infection from the nares, oral cavity and the skin.1 This comprehensive system can be used as part of your preoperative infection prevention strategy.

Standardize early prepping

Early prepping can begin on the night or nights before surgery, depending on hospital protocol. In Pre-op Holding, the Nose To Toes system can help standardize your approach for maximum efficiency and enhanced compliance to protocol. The system includes:

  • 2% Chlorhexidine Gluconate* Cloths
  • Sage Ultra-Soft Toothbrush with:
    • 3M™ Peridex™ (Chlorhexidine Gluconate 0.12%) Oral Rinse in a single dose bottle or
    • Corinz® Antiseptic Cleansing and Moisturizing Oral Rinse in a burst pouch
  • 3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation in a single dose bottle
    3M and Peridex are trademarks of 3M

Reduce SSI

A March 2015 study, published in JAMA Surgery demonstrated a greater than 50% decrease in SSI rate in patients undergoing orthopedic implant surgery after implementation of a preoperative decontamination protocol featuring chlorhexidine gluconate (CHG) cloths, intranasal povidone-iodine solution and an oral rinse.2

*equivalent to 500mg Chlorhexidine Gluconate per cloth
REFERENCES: 1. Mangram A, Horan T, Pearson M, Silver L, Jarvis W. Guideline for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol. 1999;20(4):247-280. 2. Bebko S, Green D, Awad S. Effect of a preoperative decontamination protocol on surgical site infections in patients undergoing elective orthopedic surgery with hardware implantation. JAMA Surg. 2015;150(5):390-395.

Nose to Toes Pre-Op Prepping System

Address multi-drug resistant organisms on your patient’s skin, oral cavity and nares prior to surgery

The Nose to Toes early prepping system helps address infection risk factors from three main reservoirs of bacteria: the nares, the oral cavity, and the skin.

1 NASAL PREPPING

3M
3M™ Skin and Nasal Antiseptic reduces bacterial counts in the nares in one hour, and maintains this reduction for at least 12 hours1

3M and Peridex are trademarks of 3M

REFERENCE: 1. 3M Study-05-011100 Sage

2 ORAL CLEANSING

An Ultra-Soft Toothbrush and a single dose bottle of 3M™ Peridex™ (Chlorhexidine Gluconate 0.12%) Oral Rinse or a burst pouch of Corinz® Antiseptic Cleansing and Moisturizing Oral Rinse helps remove dental plaque and provides antimicrobial activity during oral rinsing

3M and Peridex are trademarks of 3M
Label insert

3 SKIN PREPPING

9707_CHG2

Sage 2% CHG Cloths contain a rinse-free solution for effective skin antisepsis and persistence for up to 6 hours after application.

Drug Facts

Early Antiseptic Prep Strategies Help Reduce SSI Risk

Night Before Surgery

Early prepping can begin at the patient’s home. Sage® 2% CHG Prep Cloths are easy to use, which may improve compliance to the patient’s pre-surgical instructions. In a recent study published in the Journal of Knee Surgery, a 72% reduction in SSIs was achieved with application of Sage’s 2% CHG Prep Cloths the night before and morning of surgery.1

Morning of Surgery

Once patients arrive at the hospital, it is important to continue early prepping by addressing the three reservoirs of bacteria – nares, oral cavity, and skin – before the patient enters the OR. By performing early prepping in the hospital, clinicians can ensure that it gets done properly for every patient.

One investigator achieved a rate of zero SSIs by implementing a comprehensive checklist including a nasal antiseptic applied intranasally in the preoperative area and using Sage 2% CHG Cloths the night before and morning of surgery.2

REFERENCES: 1. Johnson A, Kapadia B, Daley J, Molina C, Mont M. Chlorhexidine reduces infection in knee arthroplasty. J Knee Surg. 2013; 26(03): 213-218. 2. Hogenmiller, Jette R., et al., Preventing orthopedic total joint replacement surgical site infections through a comprehensive best practice bundle/checklist. Poster presented at Association for Professionals in Infection Control and Epidemiology (APIC) June 2011.

compliance

PrepCheck Reminder System for Early PreOp Prepping

PrepCheck is a free service available to both hospitals and patients, which delivers automated reminders via email, text, or voicemail, to remind patients to perform their skin prep. PrepCheck also serves as a reminder to document skin prep completion.
prep-check

Access our Prep-Check® Reminder System for Early PreOp Prepping.

2% Chlorhexidine Gluconate* Cloth

The First FDA-Approved Preoperative Skin Prep in a Cloth

Sage 2% CHG Cloths address multi drug resistant organisms (MDROs) on the patients’ skin – a known risk factor for SSIs.1 Sage’s innovative rinse-free, alcohol-free formula is designed for early prep. It stays on the skin and provides antimicrobial activity for up to 6 hours after application. The cloth consistently delivers a uniform dose of CHG, unlike other solutions.

*equivalent to 500mg chlorhexidine gluconate per cloth

REFERENCE: 1. Mangram, AJ., Horan, TC., Pearson, ML. et al. Guideline for Prevention of Surgical Site Infection, 1999. Infection Control and Hospital Epidemiology. 1999;20(4):247-78.

No-Rinse 2% CHG Prep Cloth Leaves More CHG on Skin than 4% Solution

A study published in the American Journal of Infection Control found that 2% CHG impregnated cloths left more CHG on the skin than 4% CHG antiseptic solution.1

REFERENCES: 1. Edmiston C, Seabrook G, Johnson C, Paulson D, Beausolei C. Comparative of a new and innovative 2% chlorhexidine gluconate-impregnated cloth with 4% chlorhexidine gluconate as topical antiseptic for preparation of the skin prior to surgery. Am J Infect Control. 2007;35(2):89-96.

DOWNLOAD ORDERING CATALOG

Skin Antisepsis, Oral Cleansing, Nasal Antisepsis

3 Packages containing:

  • (2) 2% Chlorhexidine Gluconate* Cloths

1 Package containing:

  • 1 Single dose bottle of 3M™ Peridex™ (Chlorhexidine Gluconate 0.12%) Oral Rinse
  • 1 Ultra-Soft Toothbrush
  • 1 Untreated Swab

1 Package containing:

  • 1 Single dose bottle of 3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution
  • 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation
  • 4 Sterile Swabs

20 systems/case
Reorder #9011


3 Packages containing:

  • (2) 2% Chlorhexidine Gluconate* Cloths

1 Package containing:

  • 1 7ml Burst Pouch of Corinz® Antiseptic Cleansing and Moisturizing Oral Rinse
  • 1 Ultra-Soft Toothbrush
  • 1 Applicator Swab with sodium bicarbonate

1 Package containing:

  • 1 Single dose bottle of 3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation
  • 4 Sterile Swabs

20 systems/case
Reorder #9010

9012

Skin Antisepsis and Nasal Antisepsis

3 Packages containing:

  • (2) 2% Chlorhexidine Gluconate* Cloths

1 Package containing:

  • 1 Single dose bottle of 3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution
  • 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation
  • 4 Sterile Swabs

20 systems/case
Reorder #9012

9001

Skin Antisepsis and Oral Cleansing

3 Packages containing:

  • (2) 2% Chlorhexidine Gluconate* Cloths

1 Package containing:

  • 1 Single dose bottle of 3M™ Peridex™ (Chlorhexidine Gluconate 0.12%) Oral Rinse
  • 1 Ultra-Soft Toothbrush
  • 1 Untreated Swab

20 systems/case
Reorder #9001


3 Packages containing:

  • (2) 2% Chlorhexidine Gluconate* Cloths

1 Package containing:

  • 1 7ml Burst Pouch of Corinz® Antiseptic Cleansing and Moisturizing Oral Rinse
  • 1 Ultra-Soft Toothbrush
  • 1 Untreated Swab

20 systems/case
Reorder #9009

9705

2% Chlorhexidine Gluconate* Cloth

2 Cloths per package
Cloth size: 7.5” x 7.5”
96 packages/case
Reorder #9705

2 Cloths per package
Cloth size: 7.5” x 7.5”
48 packages/case
Reorder #9706

9707
3 individually wrapped packages
(2 cloths per package)
Cloth size: 7.5” x 7.5”
32 packages/case
Reorder #9707

*equivalent to 500mg Chlorhexidine Gluconate per cloth
3M and Peridex are trademarks of 3M

Clinical Support

Effect of a Preoperative Decontamination Protocol on Surgical Site Infections in Patients Undergoing Elective Orthopedic Surgery With Hardware Implantation
Serge P. Bebko MD, David M. Green MD, Samir S. Awad MD, MPH
JAMA Surgery, May 2015

Does Preadmission Cutaneous Chlorhexidine Preparation Reduce Surgical Site Infections After Total Hip Arthroplasty?
Kapadia BH, Jauregui JJ, Murray DP, Mont MA
Clinical Orthopaedics and Related Research, 2016

Preoperative shower revisited: can high topical antiseptic levels be achieved on the skin surface before surgical admission?
Edmiston CE Jr, Krepel CJ, Seabrook GR, Lewis BD, Brown KR, Towne JB.
American College of Surgeons, 2008

Preventing Staphylococcus aureus Surgical Site Infections: an Open-label, Randomized Trial of Nasal Mupirocin Ointment and Nasal Povidone-Iodine Solution (PDF)
Michael S. Phillips, MD
SHEA 2012

Click for a complete listing of clinical evidence to support your prevention efforts.

Clinical Information